Module 1.
Mouse Anatomy and Pathobiology
- Mouse status in biomedicine
- Standardized nomenclature for mice
- Anatomical and histological methods
- Mouse embryology and placenta
- Gross anatomy and topography in mouse
- Histology of mouse organs
- Ultrastructure of mouse tissues
- Ontological approach to mouse morphology
- Introduction to general mouse pathology
- Mouse necropsy Pathology of the major organ systems
- Optional language course (Spanish, Catalan)
Module 2.
Mouse Imaging
- Anatomical bases of mouse imaging
- Mouse handling, care, and anesthesia
- Imaging using ionizing radiation (X-ray, CT, SPECT, PET)
- Imaging using non-ionizing radiation (MRI, FMT, NIR, HFUS, PAI)
- Hybrid imaging (PET/CT, PET/MR, US/PAI)
- Imaging contrast agents
Applications: cell trafficking and cell tissue homing, angiogenesis, hypoxia, apoptosis and inflammation - Optional language course (Italian)
Module 3.
Deep learning and experimental design
- Introduction to deep and machine learning
- Classifiers and metrics for evaluation
- Supervised and unsupervised algorithms
- Convolutional neural and recurrent networks
- Methodologies for 1D and 2D signals: sliding windows, super-pixels, streaming data and whole pictures transformation
- Methodologies for conducting deep learning experiments
- Experimental design with mice: quantitative comparison, ARRIVE and 3Rs
- Optional language course (Greek)
Module 4.
Master’s Degree Dissertation
Short research project on anatomy, pathology, imaging and deep learning applied to the phenotyping of mouse disease models